前往化源商城

Chemistry An Asian Journal 2013-11-01

Stereoselective synthesis of highly functionalized nitrocyclopropanes through the organocatalyic Michael-addition-initiated cyclization of bromonitromethane and β,γ-unsaturated α-ketoesters.

Haijian Yu, Qiaohui Wang, Youming Wang, Haibing Song, Zhenghong Zhou, Chuchi Tang

文献索引:Chem. Asian J. 8(11) , 2859-63, (2013)

全文:HTML全文

摘要

A highly diastereo- and enantioselective cyclopropanation of β,γ-unsaturated α-ketoesters with bromonitromethane has been successfully developed through a domino Michael-addition/intramolecular-alkylation strategy. Acceptable yields (up to 89%) and enantioselectivities (up to 96% ee) have been obtained.Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

相关化合物

结构式 名称/CAS号 全部文献
溴代硝基甲烷 结构式 溴代硝基甲烷
CAS:563-70-2