Journal of the American Chemical Society 2004-04-28

Palladium-catalyzed C-H homocoupling of thiophenes: facile construction of bithiophene structure.

Kentaro Masui, Haruka Ikegami, Atsunori Mori

文献索引：J. Am. Chem. Soc. 126 , 5074, (2004)

摘要

Palladium-catalyzed C-H homocoupling of thiophene derivatives takes place in the presence of silver(I) fluoride or acetate. A variety of bithiophenes are obtained in good to excellent yields. In particular, the reaction of 2-bromothiophene proceeds at room temperature to afford 5,5'-dibromo-2,2'-bithiophene, where the bromine atom is completely intact in the palladium-catalyzed reaction. XRD analysis reveals that silver fluoride is reduced to silver(0) during the reaction.

结构式	名称/CAS号	分子式	全部文献
	双(1,4-联苯膦)丁基二氯化钯(II) CAS:29964-62-3	C₂₈H₂₈Cl₂P₂Pd

B.L. Shaw
[Chem. Commun. (Camb.) , 1863, (1998)]

M. Kranenburg et al.
[Eur. J. Inorg. Chem. , 155, (1998)]

Minato, K.; Suzuki, K et al.
[J. Chem. Soc. Chem. Commun. , 511, (1984)]

Bjork, P.; Hornfeldt, A.-B. et al.
[J. Heterocycl. Chem. 31 , 1161, (1994)]

MethCohn, O.; Jiang, H.
[J. Chem. Soc. Perkin Trans. I , 3737, (1998)]

Palladium-catalyzed C-H homocoupling of thiophenes: facile construction of bithiophene structure.

摘要

相关化合物