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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Tetrahedron Letters

Rhodium-catalyzed phenylthiolation reaction of heteroaromatic compounds using α-(phenylthio) isobutyrophenone

M Arisawa, F Toriyama, M Yamaguchi

文献索引：Arisawa, Mieko; Toriyama, Fumihiko; Yamaguchi, Masahiko Tetrahedron Letters, 2011 , vol. 52, # 18 p. 2344 - 2347

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被引用次数: 23

摘要

In the presence of catalytic amounts of RhH (PPh3) 4 and 1, 2-bis (diphenylphosphino) ethane (dppe), 1, 3-benzothiazoles, 1, 3-benzoxazoles, and benzothiophene reacted with α- (phenylthio) isobutyrophenone giving 2-phenylthio derivatives. Reactive monocyclic heteroaromatics, 1-methyl-1, 2, 3, 4-tetrazole and 2-cyanothiophene were also converted into the 5-phenylthio derivatives. The use of an appropriate phenylthio transfer reagent is ...

苯并噻唑结构式

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2-甲硫基苯并噻唑结构式

2-甲硫基苯并噻唑

1-propanone, 1-(4-methoxyphenyl)-2-methyl-结构式

1-propanone, 1-...

苯并噻唑结构式

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

~91%

2-phenylsulfanyl-1,3-benzothiazole结构式

2-phenylsulfany...

异丁酰苯结构式

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2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

~93%

2-phenylsulfanyl-1,3-benzothiazole结构式

2-phenylsulfany...

isobutyrophenone-d3结构式

isobutyrophenone-d3

硫酚结构式

~%

2-phenylsulfanyl-1,3-benzothiazole结构式

2-phenylsulfany...

苯并噻唑结构式

2-(methylthio)-1-phenyl-1-propanone结构式

2-(methylthio)-...

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2-甲硫基苯并噻唑结构式

2-甲硫基苯并噻唑

苯丙酮结构式

2-溴异丁酰苯结构式

2-溴异丁酰苯

硫酚结构式

~98%

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

苯并噻唑结构式

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~26%

2-(4-chlorophenyl)sulfanyl-1,3-benzothiazole结构式

2-(4-chlorophen...

异丁酰苯结构式

苯并噻唑结构式

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2-甲硫基苯并噻唑结构式

2-甲硫基苯并噻唑

2,4'-dimethylpropiophenone结构式

2,4'-dimethylpr...

苯并恶唑结构式

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

~0%

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异丁酰苯结构式

6-甲基苯并噻唑结构式

6-甲基苯并噻唑

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

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6-methyl-2-(phenylthio)benzo[d]thiazole结构式

6-methyl-2-(phe...

异丁酰苯结构式

6-氯苯并噻唑结构式

6-氯苯并噻唑

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

~0%

6-chloro-2-(phenylthio)benzo[d]thiazole结构式

6-chloro-2-(phe...

异丁酰苯结构式

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

6-(三氟甲基)苯并[d]噻唑结构式

6-(三氟甲基)苯并[d]噻唑

~0%

未登录结构式

异丁酰苯结构式

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

5-氯苯并恶唑结构式

5-氯苯并恶唑

~0%

5-chloro-2-phenylthio-1,3-benzoxazole结构式

5-chloro-2-phen...

异丁酰苯结构式

5-甲基苯并唑结构式

5-甲基苯并唑

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

~0%

5-methyl-2-phenylthio-1,3-benzoxazole结构式

5-methyl-2-phen...

异丁酰苯结构式

苯并[b]噻吩-3-甲腈结构式

苯并[b]噻吩-3-甲腈

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

~0%

未登录结构式

异丁酰苯结构式

6-甲氧基苯并[d]恶唑结构式

6-甲氧基苯并[d]恶唑

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

~0%

未登录结构式

异丁酰苯结构式

6-甲氧基苯并噻唑结构式

6-甲氧基苯并噻唑

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

~0%

6-Methoxy-2-(phenylthio)benzothiazole结构式

6-Methoxy-2-(ph...

异丁酰苯结构式

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

5-三氟甲基苯并噁唑结构式

5-三氟甲基苯并噁唑

~0%

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异丁酰苯结构式

苯并噻唑结构式

未登录结构式

~0%

2-(4-chlorophenyl)sulfanyl-1,3-benzothiazole结构式

2-(4-chlorophen...

异丁酰苯结构式

2-氰基噻吩结构式

2-methyl-1-phenyl-2-phenylsulfanylpropan-1-one结构式

2-methyl-1-phen...

~0%

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异丁酰苯结构式

苯并噻唑结构式

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异丁酰苯结构式

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苯丙酮结构式

~16%

苯并恶唑结构式

1-phenyl-2-(phenylthio)-1-propanone结构式

1-phenyl-2-(phe...

苯并噻唑结构式

未登录结构式

~23%

2-甲硫基苯并噻唑结构式

2-甲硫基苯并噻唑

2,4'-dimethylpropiophenone结构式

2,4'-dimethylpr...

苯并噻唑结构式

未登录结构式

~15%

2-甲硫基苯并噻唑结构式

2-甲硫基苯并噻唑

苯异丁酮结构式

苯并噻唑结构式

未登录结构式

~21%

2-甲硫基苯并噻唑结构式

2-甲硫基苯并噻唑

1-propanone, 1-(4-methoxyphenyl)-2-methyl-结构式

1-propanone, 1-...

苯并噻唑结构式

2-(methylthio)-1-phenyl-1-propanone结构式

2-(methylthio)-...

~13%

2-甲硫基苯并噻唑结构式

2-甲硫基苯并噻唑

苯丙酮结构式

苯并噻唑结构式

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~9%

2-甲硫基苯并噻唑结构式

2-甲硫基苯并噻唑

4-isobutyrylbenzonitrile结构式

4-isobutyrylben...

二苯乙酮结构式

α-(methylthio)-p-cyanoacetophenone结构式

α-(methylthio)-...

~70%

4-乙酰基苯甲腈结构式

4-乙酰基苯甲腈

2-methylsulfanyl-1,2-diphenyl-ethanone结构式

2-methylsulfany...

苯并噻唑结构式

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2-甲硫基苯并噻唑结构式

2-甲硫基苯并噻唑

苯异丁酮结构式

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