Novel 2-(2, 4-dioxo-1, 3-thiazolidin-5-yl) acetamides as antioxidant and/or anti-inflammatory compounds

…, S Avula, S Pombala, S Vasamsetti, S Kotamraju…

文献索引：Koppireddi, Satish; Komsani, Jayaram Reddy; Avula, Sreenivas; Pombala, Sujitha; Vasamsetti, Satishbabu; Kotamraju, Srigiridhar; Yadla, Rambabu European Journal of Medicinal Chemistry, 2013 , vol. 66, p. 305 - 313

全文：HTML全文

被引用次数: 12

摘要

Abstract A series of novel N-(4-aryl-1, 3-thiazol-2-yl)-2-(2, 4-dioxo-1, 3-thiazolidin-5-yl) acetamides (4a–k) and N-(1, 3-benzothiazol-2-yl)-2-(2, 4-dioxo-1, 3-thiazolidin-5-yl) acetamide derivatives (4l–o) are synthesized and evaluated for their anti-inflammatory and antioxidant activity (DPPH radical scavenging, superoxide anion scavenging, lipid peroxide inhibition, erythrocyte hemolytic inhibition). Compounds 4k and 4l have exhibited good ...