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Silica gel-Supported Palladium Catalyst for the Acyl Sonogashira Reaction

S Hossain, J Park, M Park, MJ Jin

文献索引:Hossain, Shahin; Park, Ji-Hoon; Park, Min-Kyu; Jin, Myung-Jong Journal of the Korean Chemical Society, 2013 , vol. 57, # 3 p. 411 - 415

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被引用次数: 2

摘要

The acyl Sonogashira reaction between acyl chlorides and terminal alkynes is one of the most useful method for the preparation of ynones which are important intermediates to prepare versatile pharmaceutically and biologically active heterocyclic compounds such as pyrroles, 1 pyrazoles, 2 furans, 3 furanones, 4 isoxazoles, 5 pyrimidines, 6 quinolines, 7 indolizidinones. 8 Due to the bifunctionalitiy and broad applicability of ynones an efficient, ...