The p; esent paper deals with the synthesis of several 3-halo-4-aminoquinoline derivatives as part of a general studylJ on the effect of the position of halogen atom substituents on the antimalarial act. ion of 4-dialkylaminoalkylaminoquino-line compounds. Of all the compounds studied thus far, only the 7-halo derivatives show marked antimalarial activity. It has now been found that the introduction of a second halogen atom in the $ position of th' ...
