Journal of Organic Chemistry 2002-09-06

Improved synthesis of 2,2'-bipyrimidine.

Gábor Vlád, István T Horváth

文献索引：J. Org. Chem. 67(18) , 6550-2, (2002)

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摘要

A high-yield synthesis was developed for the preparation of 2,2'-bipyrimidine (1) using the Ullmann coupling of 2-iodopyrimidine. The new procedure was also used for the preparation of 4,4',6,6'-tetramethyl-2,2'-bipyrimidine (2) and 5,5'-dibromo-2,2'-bipyrimidine (3).