Abstract: A superior method for the synthesis of substituted ethyl benzofuran-2-carboxylates in 80-99% yields from substituted 2-formylphenoxy ethylcarboxylates using 0.4 equiv of commercially available P (MeNCH2CH2) 3N at 70 C for 3 hours is described. Key words: benzofurans, bicyclic compounds, catalysis, cyclizations, heterocyclics
[Chapleo, Christopher B.; Myers, Peter L.; Butler, Richard C. M.; Davis, John A.; Doxey, John C.; et al. Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 570 - 576]