Synthetic Communications

Facile and versatile synthesis of alkyl and aryl isothiocyanates by using triphosgene and cosolvent

P Liu, C Li, J Zhang, X Xu

文献索引：Liu, Pengfei; Li, Chunyan; Zhang, Jingwei; Xu, Xiaoyong Synthetic Communications, 2013 , vol. 43, # 24 p. 3342 - 3351

全文：HTML全文

被引用次数: 5

摘要

A mild and efficient method for the conversion of alkyl and aryl amines to isothiocyanates via dithiocarbamates has been developed using (CH 3 ) 2 CO-CS 2 as co-solvent and triphosgene as dehydrosulfurization reagent. High yields, mild reaction conditions and excellent functional group compatibility make it become a versatile synthetic method for the preparation of isothiocyanates compared with reported methods. ... [Supplementary materials are available for this ...