Tetrahedron Letters

A novel route to synthesis of flavones from salicylaldehyde and acetophenone derivatives

KV Sashidhara, M Kumar, A Kumar

文献索引：Sashidhara, Koneni V.; Kumar, Manoj; Kumar, Abdhesh Tetrahedron Letters, 2012 , vol. 53, # 18 p. 2355 - 2359

全文：HTML全文

被引用次数: 23

摘要

Convenient, facile, and alternate synthesis of medicinally important flavones is reported. The 2-hydroxychalcones derived from condensation between acetophenones and salicylaldehyde, underwent oxidative cyclization on heating in the presence of catalytic iodine, generating diversified flavones under solvent-free conditions. Eleven compounds have been synthesized in good to excellent yields and their mechanism of formation is ...