A novel family of aromatic diazirines for photoaffinity labeling

…, M Hashimoto, H Kurihara, H Nakayama…

文献索引：Hatanaka, Yasumaru; Hashimoto, Makoto; Kurihara, Hiroko; Nakayama, Hitoshi; Kanaoka, Yuichi Journal of Organic Chemistry, 1994 , vol. 59, # 2 p. 383 - 387

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被引用次数: 113

摘要

A series of simple methods for modifying diazirines bearing an aromatic ring has been accomplished. This first versatile approach involving direct substitution on the aromatic ring of diazirines has been achieved by means of the aromatic thallation of (alkoxypheny1) diazirines. Introduction of the thallium moiety was successfully followed by nitration, iodination, or palladium-catalyzed carbonylation to give a family of substituted ...