Functionalized 1, 2-dioxetanes as potential phototherapeutic agents: the synthesis of carboxylate, carbonate, carbamate, and ether derivatives of 3-(hydroxymethyl)-3, …

…, V Bhushan, R Fuchs, U Kirchgaessner

文献索引：Adam, Waldemar; Bhushan, Vydia; Fuchs, Rainer; Kirchgaessner, Uwe Journal of Organic Chemistry, 1987 , vol. 52, # 14 p. 3059 - 3062

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被引用次数: 6

摘要

With gentle and efficient synthetic methods, 3-(hydroxymethyl)-3, 4, 4-trimethyl-l, Z- dioxetane(1) can be transformed with appropriate electrophiles in moderate to good yields into functionalized derivatives of dioxetane 1. As electrophiles served carboxylic acids, chlorocarbonates, isocyanates, trialkyloxonium salts, and trialkylsilyl chlorides. With 1 these afford respectively dioxetanes with carboxylate, carbonate, carbamate, ether, and silyl ...