The process development of ravuconazole: an efficient multikilogram scale preparation of an antifungal agent (1)

…, D Berglund, J Bien, P Brodfuehrer…

文献索引：Olah, George A.; Prakash, G. K. Surya; Arvanaghi, Massoud; Bruce, Mark R. Angewandte Chemie, 1981 , vol. 93, # 1 p. 107

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被引用次数: 17

摘要

... Volume: Page: ... This sequence also sets the second chiral center, effectively originating all stereogenic centers from methyl (R)-lactate. ... the sulfur ylide, followed by the addition of the substrate 7.(7) The adjacent chiral center induced an ∼4:1 stereoselectivity for ...