Abstract An efficient protocol was developed for regio-selective Pd-catalyzed direct ortho- fluorination of 2-arylbenzo [d] thiazoles using N-fluorobenzenesulfonimide (NFSI) as the F+ source, and l-proline as the crucial promoter. The present method offered a practical route to synthesize valuable fluorinated products, which are of potential importance in the pharmaceutical and agrochemical industries.
