Copper-mediated N-and O-arylations with arylboronic acids in a continuous flow microreactor: a new avenue for efficient scalability
…, DRJ Acke, VS Parmar, EV Van der Eycken
文献索引:Singh, Brajendra K.; Stevens, Christian V.; Acke, Davy R.J.; Parmar, Virinder S.; Van der Eycken, Erik V. Tetrahedron Letters, 2009 , vol. 50, # 1 p. 15 - 18
A continuous flow procedure has been elaborated for the copper (II)-mediated N-and O- arylation of a range of compounds with arylboronic acids using a commercial microreactor setup. The compounds could be continuously generated in good yields paving the way for efficient scalability.