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p–Aminobenzoic acid derivatives as acetylcholinesterase inhibitors

…, LM Espinoza-Fonseca, JG Trujillo-Ferrara

文献索引:Correa-Basurto, Jose; Alcantara, Ivan Vazquez; Espinoza-Fonseca, L. Michel; Trujillo-Ferrara, Jose G. European Journal of Medicinal Chemistry, 2005 , vol. 40, # 7 p. 732 - 735

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被引用次数: 27

摘要

Because Alzheimer's disease (AD) is a medical problem characterized by progressive loss of memory and cognition that is associated with a deficient cholinergic system, this work aims to evaluate some p-aminobenzoic acid (PABA) derivatives as acetylcholinesterase inhibitors in vitro, in continuation with our last studies. The assayed compounds are low toxic, simple-structured and low cost.