The Journal of organic chemistry

One-Pot Synthesis of 1-and 2-Substituted Naphtho [2, 3-d][1, 2, 3] triazole-4, 9-diones

J Zhang, CWT Chang

文献索引：Zhang, Jianjun; Chang, Cheng-Wei Tom Journal of Organic Chemistry, 2009 , vol. 74, # 11 p. 4414 - 4417

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被引用次数: 15

摘要

A one-pot three-component [2+ 3] cycloaddition for the synthesis of 1-alkyl 1 H-naphtho [2, 3- d][1, 2, 3] triazole-4, 9-dione and 2-alkyl 2 H-naphtho [2, 3-d][1, 2, 3] triazole-4, 9-dione has been developed. By taking the advantage of difference in basicity, both products can be obtained in good purity. The unique heterocyclic scaffolds of these two products could exert interesting chemical and biological properties. The synthetic protocol is concise and ...