Organic letters

Small peptides catalyze highly enantioselective direct aldol reactions of aldehydes with hydroxyacetone: unprecedented regiocontrol in aqueous media

Z Tang, ZH Yang, LF Cun, LZ Gong, AQ Mi…

文献索引：Organic Letters, , vol. 6, # 13 p. 2285 - 2287

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被引用次数: 218

摘要

... Organic Letters. ... g Performed with 10 mol % catalyst 4; reaction temperature = 0 °C; v/v of hydroxyacetone/solvent = 1/2 (1/3 vol hydroxyacetone); reaction time = 6 days. ... Table 2. Direct Aldol Reactions of Acetone with Aldehydes by Chiral Organic Catalyst 3 a or 4 b. ...