Serotoninergic properties of new conformationally restricted benzamides

…, B Bremont, S Shen, S Kefi, M Langlois

文献索引：Yang; Bremont; Shen; Kefi; Langlois European Journal of Medicinal Chemistry, 1996 , vol. 31, # 3 p. 231 - 239

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被引用次数: 11

摘要

A new series of benzamides derived from metoclopramide have been synthesized, in which the vicinal carbon of the basic nitrogen atom of the ethyl chain is situated on the C3, C4, C5 and C6 rings. The diamino derivatives were prepared through Strecker's reaction from the corresponding ketones except for the cyclopropyl derivatives where 1-ethoxy-1- trimethylsiloxy cyclopropane was used as the starting material. The benzamides were ...