Molecules 2012-01-01

Allylation of functionalized aldehydes by potassium allyltrifluoroborate catalyzed by 18-crown-6 in aqueous media.

Fernanda C G Barbosa, Juliano C R Freitas, Caio F Melo, Paulo H Menezes, Roberta A Oliveira

文献索引：Molecules 17(12) , 14099-110, (2012)

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摘要

An efficient method for the allylation of aldehydes containing a broad range of functional groups using potassium allyltrifluoroborate is described. The reaction utilizes a catalytic amount of 18-C-6 in biphasic media under open atmosphere and room temperature to provide the corresponding homoallylic alcohols in high yields and without the necessity of any subsequent purification.