The discovery of tetrahydro-β-carbolines as inhibitors of the kinesin Eg5

PA Barsanti, W Wang, ZJ Ni, D Duhl…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 1 p. 157 - 160

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被引用次数: 54

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Molecular modeling and medicinal chemistry techniques were employed to explore the SAR for this series with a focus of removing potential metabolic liabilities and improving cellular potency. ...