前往化源商城

Synthesis and anti-norovirus activity of pyranobenzopyrone compounds

L Pokhrel, Y Kim, TDT Nguyen, AM Prior, J Lu…

文献索引:Pokhrel, Laxman; Kim, Yunjeong; Nguyen, Thi D.T.; Prior, Allan M.; Lu, Jianyu; Chang, Kyeong-Ok; Hua, Duy H. Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 10 p. 3480 - 3484

全文:HTML全文

被引用次数: 17

摘要

During the last decade, noroviruses have gained media attention as the cause of large scale outbreaks of gastroenteritis on cruise ships, dormitories, nursing homes, etc. Although noroviruses do not multiply in food or water, they can cause large outbreaks because approximately 10–100 virions are sufficient to cause illness in a healthy adult. Recently, it was shown that the activity of acyl-coenzyme A: cholesterol acyltransferase-1 (ACAT1) ...