Bollettino della Societa italiana di biologia sperimentale 1984-01-30

[Reaction products of indandione with ethyl alpha-cyano-beta-acrylates].

M V Diurno, G Cirino, A Squassi

文献索引：Boll. Soc. Ital. Biol. Sper. 60(1) , 79-84, (1984)

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摘要

In order to obtain biologically active compounds with a probable anticoagulant activity, some new products, by Michael method from indandione and 2-phenylindandione with ethyl alpha-cyano-beta-aryl-acrylates, have been prepared. The reaction of phenylindandione with methylvinylketone has been also carried out. The products have been characterized by chemical analysis and spectral determinations. The products showed an anticoagulant activity "in vitro" in a preliminary pharmacological screening.