A criteria to classify biological activity of benzimidazoles from a model of structural similarity

M Niño, EE Daza C, M Tello

文献索引：Norman, Mark H.; Navas III, Frank; Thompson, James B.; Rigdon, Greg C. Journal of Medicinal Chemistry, 1996 , vol. 39, # 24 p. 4692 - 4703

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被引用次数: 14

摘要

We have classified a set of 250 benzimidazoles using a criterion of structural similarity. This criterion has led us to several clusters, which keep a close relationship between the molecules belonging to each one of them and their pharmacological activity. To study the