Bioorganic & Medicinal Chemistry Letters 2009-01-01

O-SpiroC-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors

Baihua Xu, Binhua Lv, Yan Feng, Ge Xu, Jiyan Du, Ajith Welihinda, Zelin Sheng, Brian Seed, Yuanwei Chen, Baihua Xu, Binhua Lv, Yan Feng, Ge Xu, Jiyan Du, Ajith Welihinda, Zelin Sheng, Brian Seed, Yuanwei Chen

文献索引：Bioorg. Med. Chem. Lett. 19(19) , 5632-5, (2009)

全文：HTML全文

摘要

Two series of O-spiro C-aryl glucosides have been synthesized and evaluated for inhibition of hSGLT1 and hSGLT2.