Isothiazoloquinolones with enhanced antistaphylococcal activities against multidrug-resistant strains: effects of structural modifications at the 6-, 7-, and 8-positions

Q Wang, E Lucien, A Hashimoto…

文献索引：Journal of Medicinal Chemistry, , vol. 50, # 2 p. 199 - 210

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被引用次数: 32

摘要

... Journal of Medicinal Chemistry. ... Chemistry. Overview. We prepared the target carbon-coupled ITQs via Suzuki−Miyaura cross-coupling of halides 1−4 with the desired boronic acids or dioxaborolanes (Scheme 1 and ...