前往化源商城

Clinical Nephrology 1996-04-01

Indoxyl-beta-D-glucuronide and 3-indoxyl sulfate in plasma of hemodialysis patients.

S Agatsuma, H Sekino, H Watanabe

文献索引:Clin. Nephrol. 45(4) , 250-6, (1996)

全文:HTML全文

摘要

The content of indoxyl-beta-D-glucuronide, which has been found in patients' plasma as a new indicator of renal failure, logarithmically correlated with that of 3-indoxyl sulfate (indican) in the plasma of hemodialysis patients, showing another weak correlation with beta(2)-microglobulin content. The content ratio of indoxyl-beta-D-glucuronide to 3-indoxyl sulfate (IG/IS) gradually increased depending on the duration of hemodialysis treatment. Indoxyl-beta-D-glucuronide could be easily dialyzed in the hemodialysis treatment, in contrast to hardly dialyzable 3-indoxyl sulfate which bound to plasma proteins. Therefore, glucuronide conjugation in indole excretion is favorable for hemodialysis patients in that it eliminates indoxyl compounds in blood by hemodialysis.

相关化合物

结构式 名称/CAS号 全部文献
3-吲哚基-beta-D-葡糖苷酸环己胺盐 结构式 3-吲哚基-beta-D-葡糖苷酸环己胺盐
CAS:35804-66-1