Antioxidant properties of 3-hydroxycoumarin derivatives

…, C Maurin, E Teissier, H Vezin, P Cotelle

文献索引：Bailly, Fabrice; Maurin, Cedric; Teissier, Elisabeth; Vezin, Herve; Cotelle, Philippe Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 21 p. 5611 - 5618

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被引用次数: 43

摘要

A series of hydroxylated 3-hydroxycoumarins was synthesised by the reaction of 3-aryl-2- hydroxypropenoic derivatives with boron tribromide. They were evaluated for their ability to scavenge the 2, 2-diphenyl-1-picrylhydrazyl radical, the superoxide anion radical, the hydroxyl radical and the peroxynitrite anion and to inhibit copper-induced human LDL peroxidation. The physicochemical results were in accordance to establish the ...