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International Journal of Peptide and Protein Reseach 1992-03-01

"Carba" peptide bond surrogates. Different approaches to Gly-psi(CH2-CH2)-D,L-Xaa pseudo-dipeptide units.

M Rodriguez, A Heitz, J Martinez

文献索引:Int. J. Pept. Protein Res. 39(3) , 273-7, (1992)

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摘要

Racemic "carba" pseudo-dipeptide units such as Gly-psi(CH2-CH2)-D,L-Xaa were obtained either through the Horner-Emmons condensation of N-tert.-butyloxycarbonyl-beta alaninal with the appropriate substituted triethyl phosphonacetate, or from commercially available 3-carbethoxy-2-piperidone.

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