Efficient Horner–Wadsworth–Emmons intramolecular cyclisation of a N-substituted phthalimide promoted by KF-Alumina: a general tool for the synthesis of …

…, CI Nova, M Fernández, JV Sinisterra, AR Alcántara

文献索引：Pace, Vittorio; Martinez, Fernando; Fernandez, Maria; Sinisterra, Jose V.; Alcantara, Andres R. Organic Letters, 2007 , vol. 9, # 14 p. 2661 - 2664

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被引用次数: 24

摘要

An intramolecular Horner–Wadsworth–Emmons reaction promoted by KF-Alumina involving a N-substituted phthalimide, cleanly and efficiently furnishes an interesting α, β-unsaturated tricyclic enone which may undergo selective alkylations at the α′-position.