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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

The effects of substituting tetrazole for carboxyl in two series of anti??inflammatory phenoxyacetic acids

…, M Horlington, JGB Howes, JM Scruton…

文献索引：Drain; Daly; Davy; Horlington; Howes; Scruton; Selway The Journal of pharmacy and pharmacology, 1970 , vol. 22, # 9 p. 684 - 693

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被引用次数: 12

摘要

Series of o-phenylcarbamoyl-and o-benzamido-phenoxymethyl tetrazoles and o- phenylcarbamoylphenoxyacetic acids have been synthesized. Anti-inflammatory activity was measured by the phenyl benzoquinone writhing test in mice and the rat foot carrageenan oedema test. Potency in the two o-benzamido substituted series could not be related with structure in a satisfactory manner. Introduction of substituents into the benzene rings of the ...

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