Organic Letters 2012-06-01

Asymmetric pericyclic cascade approach to spirocyclic oxindoles.

Edward Richmond, Nicolas Duguet, Alexandra M Z Slawin, Tomáš Lébl, Andrew D Smith

文献索引：Org. Lett. 14(11) , 2762-5, (2012)

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摘要

The reaction of chiral N-arylnitrones with carbocyclic alkylarylketenes generates spirocyclic oxindoles in good yields and with excellent levels of enantioselectivity (90-99% ee) via a pericyclic cascade process.