Journal of the American Chemical Society 2006-01-11

Total synthesis of ecteinascidin 743.

Jinchun Chen, Xiaochuan Chen, Michèle Bois-Choussy, Jieping Zhu

文献索引：J. Am. Chem. Soc. 128(1) , 87-9, (2006)

全文：HTML全文

摘要

A convergent total synthesis of ecteinascidin 743 is realized from five building blocks of almost equal size. It takes 23 steps from l-3-hydroxy-4-methoxy-5-methyl phenylalanol (5) with an overall yield of 3%.