Synthesis of novel functionalized 5-nitroisoquinolines and evaluation of in vitro antimalarial activity

…, MP Crozet, P Timon-David, J Maldonado

文献索引：Rathelot; Vanelle; Gasquet; Delmas; Crozet; Timon-David; Maldonado European Journal of Medicinal Chemistry, 1995 , vol. 30, # 6 p. 503 - 508

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被引用次数: 43

摘要

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Novel aldimine and hydrazone isoquinoline derivatives were obtained after subjecting 1-formyl-5-nitroisoquinoline to classical reactions. Some of these compounds were found to have activity against a chloroquine-resistant Plasmodium falciparum strain (ACC Niger).