The Lithium Aluminum Hydride Reduction of Some N-Substituted Succinimides1

KC SCHREIBER, VP FERNANDEZ

文献索引：Schreiber,K.C.; Fernandez,V.P. Journal of Organic Chemistry, 1961 , vol. 26, p. 1744 - 1747

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被引用次数: 29

摘要

The reduction of a number of N-substituted succinimides with lithium aluminum hydride has been studied. In all but one case reduction to the N-substituted pyrrolidines occurs smoothly. N-Benzhydryl, Nt-butyl and N-phenylsuccinimides undergo ring opening to yield the respective amino alcohols in addition to the normal reduction product. N-Tritylsuccinimide gives only N-trityl-4hydroxybutyramide. Several succininamic acids have been reduced to ...