The Journal of Organic Chemistry

Reductive cleavage of aromatic disulfides using a polymer-supported phosphine reagent

RA Amos, SM Fawcett

文献索引：Amos, Richard A.; Fawcett, Shayne M. Journal of Organic Chemistry, 1984 , vol. 49, # 14 p. 2637 - 2639

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被引用次数: 22

摘要

While the reaction as described is quite clean and affords high yields, it does necessitate the separation of the thiol from the triphenylphosphine oxide byproduct and any excess phosphine. The method we now wish to describe utilizes polystyryldiphenylphosphine as a polymer-supported phosphine reagent. 12 The aromatic disulfide is dissolved in an aqueous THF solution containing a catalytic amount of HC1, followed by the addition of the ...