Total Synthesis of (+)-Ambruticin S: Probing the Pharmacophoric Subunit†

S Hanessian, T Focken, X Mi, R Oza…

文献索引：Hanessian, Stephen; Bennani, Youssef L.; Leblanc, Yves Heterocycles, 1993 , vol. 35, # 2 p. 1411 - 1424

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被引用次数: 25

摘要

An enantioselective synthesis of the antifungal natural product (+)-ambruticin S has been accomplished starting with the readily available methyl α-d-glucopyranoside,(R)-Roche ester, and (S)-glycidol as chirons, which encompassed seven of the 10 stereogenic centers