Amino Acids. XV. Michael Addition Reactions of Diethyl Acetamidomalonate1

GH Cocolas, WH Hartung

文献索引：Cocolas; Hartung Journal of the American Chemical Society, 1957 , vol. 79, p. 5203

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被引用次数: 12

摘要

Since the formation of a pyrrolidinolie from a Michael addition is unexpected, a consideration of a possible manner in which the cyclization occurs may shed light on the feasibility of such a reaction. The occurrence of cyclic products resulting during the course of a Michael addition is not new. Connor and McClellan13 state that ring closures can occur if the reaction is carried out under reflux conditions. &o, these conditions are favorable for ...