| 常用名 | 戈米辛A | CAS号 | 58546-54-6 |
|---|---|---|---|
| 价格 | ¥500.0/20mg | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 900 mg |
| 产品详情(用途,包装等)
用途: Schisandrol B is one of its major active constituents of traditional hepato-protective Chinese medicine, Schisandra sphenanthera.IC50 value:Target:in vitro: SolB pretreatment significantly attenuated the increases in alanine aminotransferase and aspartate aminotransferase activity, and prevented elevated hepatic malondialdehyde formation and the depletion of mitochondrial glutathione (GSH) in a dose-dependent manner. SolB also dramatically altered APAP metabolic activation by inhibiting the activities of CYP2E1 and CYP3A11, which was evidenced by significant inhibition of the formation of the oxidized APAP metabolite NAPQI-GSH [1]. SolB abrogated APAP-induced activation of p53 and p21, and increased expression of liver regeneration and antiapoptotic-related proteins such as cyclin D1 (CCND1), PCNA, and BCL-2. 物理化学性质: CAS号:58546-54-6 常用中文名:戈米辛A 常用英文名:Gomisin A 分子式:C23H28O7 分子量:416.464 密度:1.2±0.1 g/cm3 沸点:579.7±50.0 °C at 760 mmHg 熔点:88.5°C 闪点:304.4±30.1 °C 储存条件:-20°C;避免加热 |