| 常用名 | 克拉利宾 | CAS号 | 4291-63-8 |
|---|---|---|---|
| 价格 | ¥需询单/1000mg ¥需询单/100g | 纯度 | 99.0% |
| 备货期 | 需询单 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Cladribine is an adenosine deaminase inhibitor used to treat hairy cell leukemia and multiple sclerosis. Target: Adenosine DeaminaseCladribine possesses concentration-dependent apoptosis-inducing potential in the HSB2 cells. Cladribine inhibits growth of primary mast cell (MC) and the MC line HMC-1 in a dose-dependent manner, with lower IC50 values recorded in HMC-1.2 cells harboring KIT D816V compared to HMC-1.1 cells lacking KIT D816V. Cladribine (0.7-3.5 mM) and/or diltiazem (2.4 mM), is injected intraperitoneally into adult zebrafish and red blood cell (RBC) lysates are assayed by HPLC for levels of purine nucleotides (e.g. ATP), potential biomarkers of cardiovascular health. Diltiazem increased RBC ATP concentrations, which are inhibited by co-injection of cladribine. 物理化学性质: CAS号:4291-63-8 常用中文名:克拉利宾 常用英文名:Cladribine 分子式:C10H12ClN5O3 分子量:285.687 密度:2.0±0.1 g/cm3 沸点:547.6±60.0 °C at 760 mmHg 熔点:181-185 °C(lit.) 闪点:285.0±32.9 °C 储存条件:2-8°C |