| 常用名 | 菊苣酸 | CAS号 | 70831-56-0 |
|---|---|---|---|
| 价格 | ¥需询单/20mg | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 900 mg |
| 产品详情(用途,包装等)
用途: L-Chicoric acid is an inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase in vitro and of HIV-1 replication in tissue culture. IC50 value:Target:In vitro: Using quantitative real-time polymerase chain reaction (PCR), l-CA inhibits integration at concentrations from 500 nM to 10 μM but also inhibits entry at concentrations above 1 μM [1]. l-Chicoric acid, an inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase, improves on the in vitro anti-HIV-1 effect of Zidovudine plus a protease inhibitor (AG1350) [2]. L-chicoric acid inhibits integrase and that the drug is likely to interact at residues near the catalytic triad in the integrase active site [3].In vivo: 物理化学性质: CAS号:70831-56-0 常用中文名:菊苣酸 常用英文名:Chicoric acid 分子式:C22H18O12 分子量:474.371 密度:1.6±0.1 g/cm3 沸点:785.0±60.0 °C at 760 mmHg 熔点:206 °C 闪点:272.9±26.4 °C 储存条件:−20°C |