| 常用名 | 帕瑞昔布 | CAS号 | 198470-84-7 |
|---|---|---|---|
| 价格 | ¥需询单/1kg | 纯度 | 99.0% |
| 备货期 | 需询单 | 库存 | 现货 |
| 产品详情(用途,包装等)
用途: Parecoxib is a potent and selective COX-2 inhibitor.IC50 value:Target: COX-2in vitro: The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue [1].in vivo: Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days [2]. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision [3]. 物理化学性质: CAS号:198470-84-7 常用中文名:帕瑞昔布 常用英文名:parecoxib 分子式:C19H18N2O4S 分子量:370.422 密度:1.3±0.1 g/cm3 沸点:N/A 熔点:148.9-151° 闪点:N/A 储存条件:<0°C;避免加热 |