盐酸小檗碱
更新时间：2025-09-20 20:28:23
| 常用名 | 盐酸黄连素； 盐酸小檗碱 | CAS号 | 633-65-8 |
|---|---|---|---|
| 价格 | ￥500.0/1kg | 纯度 | 97.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Berberine has shown to be effective in inhibiting cell proliferation and promoting apoptosis in various cancerous cells; MAPK and Wnt/β-catenin pathways affected by Berberine.IC50 value:Target: Anticancer agentThe plant-based alkaloid berberine has potential therapeutic applications for breast cancer, although a better understanding of the genes and cellular pathways regulated by this compound is needed to define the mechanism of its action in cancer treatment. In this review, the molecular targets of berberine in various cancers, particularly breast cancer, are discussed. Berberine was shown to be effective in inhibiting cell proliferation and promoting apoptosis in various cancerous cells. Some signaling pathways affected by berberine, including the MAP (mitogen-activated protein) kinase and Wnt/β-catenin pathways, are critical for reducing cellular migration and sensitivity to various growth factors [1]. Treatment with BBR(Berberine) in rats on the atherogenic diet reduced plasma total cholesterol and nonHDL cholesterol levels by 29%-33% and 31%-41%, respectively, with no significant differences being observed among the three doses [2]. Berberine induced both apoptotic and autophagic death of HepG2 cells, which was associated with a significant activation of AMPK and an increased expression of the inactive form of acetyl-CoA carboxylase (ACC) [3]. Berberine did not show major effects on viability of HEK-293 embryonic kidney and HCT116 colon carcinoma cells and was not toxic in concentrations up to 20 μM. Berberine inhibited β-catenin transcriptional activity and attenuated anchorage-independent growth. As a result of berberine treatment, cellular levels of active β-catenin were reduced concomitant with an increase in the expression of E-cadherin [4]. 物理化学性质： CAS号：633-65-8 常用中文名：盐酸黄连素； 盐酸小檗碱 常用英文名：Berberine hydrochloride 分子式：C20H18ClNO4 分子量：372.822 密度：1.654g/cm3 沸点：N/A 熔点：200ºC 闪点：N/A 储存条件：低温通风低干燥,与库房食品原料分开存放 |
- 上海化源生化科技有限公司
- 上海市 上海市 普陀区
- 产品名：盐酸小檗碱
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：盐酸小檗碱
- 价格： ￥138.0/20mg ￥168.0/5g ￥568.0/25g
- 纯度：98.0%
- 备货期：需询单
- 联系人：刘佳
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：盐酸小檗碱
- 价格： ￥569.9/100mg ￥1249.9/1g ￥949.9/500mg ￥399.9/50mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
- 武汉敬康恩生物医药科技有限公司
- 湖北省 武汉市 东西湖区
- 产品名：Berberine hydrochloride
- 价格： ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：周经理
- 盼得（上海）国际贸易有限公司
- 上海市 上海市 徐汇区
- 产品名：盐酸小碱(黄连素)(植物提取)
- 价格： ￥需询单/500g ￥需询单/1kg ￥需询单/25kg ￥需询单/200kg
- 纯度：0.0%
- 备货期：需询单
- 联系人：叶经理
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参考价格：$66/100mg