多奈哌齐
更新时间：2025-11-06 10:21:17
| 常用名 | 多萘哌齐碱 | CAS号 | 120014-06-4 |
|---|---|---|---|
| 价格 | ￥需询单/1kg ￥需询单/100g ￥需询单/100kg ￥需询单/1ton | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Donepezil(E 2020) is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM, respectively.Target: AChEDonepezil is a specific and potent AChE inhibitor for bAChE and hAChE with IC50 of 8.12 nM and 11.6 nM , respectively [1]. Donepezil inhibits the carbachol-stimulated increase in intracellular Ca2+ concentration in human SHSY5Y neuroblastoma cells in a concentration dependent manner, indicating that Donepezil have muscarinic antagonist activity. Intraperitoneal administration of Donepezil in rats produces a dose dependent increase in salivation and tremor, which are overt cholinergic behavioural signs, with an ED50 of 6 μmol/kg. Donepezil is found to be somewhat less potent with a ED50 of 50 μmol/kg following oral administration [2]. A recent study shows that Donepezil can protect human umbilical vein endothelial cells (HUVECs) against H2O2-induced cell injury. This may be useful as a potential therapy for oxidative stress in cardiovascular and cerebrovascular diseases [3]. 物理化学性质： CAS号：120014-06-4 常用中文名：多萘哌齐碱 常用英文名：donepezil 分子式：C24H29NO3 分子量：379.492 密度：1.1±0.1 g/cm3 沸点：527.9±50.0 °C at 760 mmHg 熔点：207ºC 闪点：273.1±30.1 °C 储存条件：室温 |
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：1-苄基-4-[(5,6-二甲氧基茚满酮-2-基)甲基]哌啶
- 价格： ￥2258.0/100mg ￥688.0/25mg
- 纯度：98.0%
- 备货期：2天
- 联系人：刘佳
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Donepezil
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：多萘哌齐碱
- 价格： ￥917.9/100mg ￥2915.9/1g ￥343.9/25mg ￥308.9/1ml
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：￥141.6/5g