(Z)-2-(11-(3-(dimethylamino)propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl)acetic acid hydrochloride
更新时间：2024-08-21 17:52:17
| 常用名 | 盐酸奥洛他定 | CAS号 | 140462-76-6 |
|---|---|---|---|
| 价格 | ￥需询单/1g | 纯度 | 98.0% |
| 备货期 | 需询单 | 库存 | 询单 |
| 产品详情（用途，包装等）
用途： Olopatadine HCl is a histamine blocker used to treat allergic conjunctivitis.Target: Histamine ReceptorOlopatadine is one of the second-generation histamine H1 receptor antagonists that are treated for allergic disorders. Olopatadine significantly inhibited the ear swelling and the increased production of IL-4, IL-1beta, IL-6, GM-CSF and NGF in the lesioned ear [1]. Olopatadine was highly and rapidly absorbed in healthy human volunteers. The urinary excretion of olopatadine accounted for not less than 58% and the contribution of metabolism was considerably low in the clearance of olopatadine in humans. Olopatadine is one of the few renal clearance drugs in antiallergic drugs. Olopatadine was shown to be useful for the treatment of allergic rhinitis and chronic urticaria in double-blind clinical trials [2]. AL-4943A inhibits histamine release in a concentration-dependent fashion (IC50 = 559 microM) from human conjunctival mast cell preparations in vitro. Passive anaphylaxis in guinea pig conjunctiva was attenuated by AL-4943A applied 30 min prior to intravenous or topical ocular antigen challenge (ED50 values 0.0067% and 0.0170%, w/v, respectively) [3]. 物理化学性质： CAS号：140462-76-6 常用中文名：盐酸奥洛他定 常用英文名：Olopatadine Hydrochloride 分子式：C21H24ClNO3 分子量：373.873 密度：1.221 g/cm3 沸点：523ºC at 760mmHg 熔点：242-245ºC 闪点：270.1ºC 储存条件：Refrigerator |
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：盐酸奥洛他定
- 价格：
- 纯度：99.0%
- 备货期：10天
- 联系人：徐经理
- 南通润丰石油化工有限公司
- 江苏省 南通市 崇川区
- 产品名：盐酸奥洛他定
- 价格： ￥需询单/1kg ￥需询单/25kg ￥需询单/200kg
- 纯度：0.0%
- 备货期：1天
- 联系人：曹经理
- 盼得（上海）国际贸易有限公司
- 上海市 上海市 徐汇区
- 产品名：盐酸奥洛他定
- 价格： ￥需询单/500g ￥需询单/1kg ￥需询单/25kg ￥需询单/200kg
- 纯度：0.0%
- 备货期：需询单
- 联系人：叶经理
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参考价格：$66/10mM*1mLinDMSO