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苯妥英钠

更新时间:2026-01-01 13:00:56

常用名 苯妥英钠 CAS号 630-93-3
价格 ¥需询单/25kg 纯度 98.0%
备货期 需询单 库存 询单
 产品详情(用途,包装等)
用途:
Phenytoin sodium is an inactive voltage-gated sodium channel stabilizer.Target: Sodium ChannelPhenytoin sodium is an antiepileptic drug. It is useful to treat partial seizures and generalized tonic-clonic seizures but not primary generalized seizures such as absence seizures or myoclonic seizures. Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage-gated sodium channels [1]. Phenytoin has low affinity for resting sodium channels at hyperpolarized membrane potentials [2]. When neurons are depolarized and the channels transition into the open and inactivated states, greater binding and block occur. The inhibitory potency is strongly use dependent, so that block accumulates with prolonged or repetitive activation, such as occurs during a seizure discharge. The blocking of sodium channels by phenytoin is of slow onset. The time course of fast sodium currents is therefore not altered in the presence of the drug and action potentials evoked by synaptic depolarizations of ordinary duration are not blocked. Thus phenytoin is able to selectively inhibit pathological hyperexcitability in epilepsy without unduly impairing ongoing activity. Phenytoin also blocks persistent sodium current and this may be of particular importance in seizure control. Phenytoin is a class 1b antiarrhythmic [3].
物理化学性质:
CAS号:630-93-3
常用中文名:苯妥英钠
常用英文名:Phenytoin sodium
分子式:C15H11N2NaO2
分子量:274.250
密度:N/A
沸点:428.2ºC at 760 mmHg
熔点:290-299ºC
闪点:212.8ºC
储存条件:室温

供应商信息

广州佰瑞医药有限公司

认证状态:未认证供应商
电话:020-37651955
地址:广州市海珠区新港中路397号自编76、77号B4-02
地区: 广东省 广州市 海珠区
联系人:刘鹏虎
联系人电话:18028682016
邮件:dylan@gzbr.com.cn
网址:http://www.gzbr.com.cn/
主要市场:
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佰瑞医药成立于2001年,是一家具GSP资质、以医药原料进出口、药品进口注册、一致性评价服务、原研参比制剂、PEG及其衍生物、BIA整体分离柱等为主要业务模块的医药产品供应链服务企业,秉持“诚信、专业、信任、高效”的经营理念及以“让世界爱上药品‘中国制造’”的使命,致力于推动药品“中国制造” 国际化,持续服务于国内的医药企业,将更多、更高性价比的优质产品和技术服务输送到中国。公司是多家国外知名药企在中国的授权总代理,拥有专业、高效的市场营销团队、技术团队和注册团队,团队成员均拥有药学相关专业背景,具丰富的国内外资源和网络,能够在业务开拓、采购销售、物流仓储、技术支持等环节给予客户最快速、最专业的一站式解决方案。
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参考价格:$66/10mM*1mLinDMSO
其他供应商价格:
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