蟾毒灵
更新时间：2024-04-05 16:17:41
| 常用名 | 蟾毒灵 | CAS号 | 465-21-4 |
|---|---|---|---|
| 价格 | ￥560.0/20mg | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 900 mg |
| 产品详情（用途，包装等）
用途： Bufalin a major digoxin-like immunoreactive component of the Chinese medicine Chan Su; has been shown to exert a potential for anticancer activity against various human cancer cell lines in vitro.IC50 value:Target: Anticaner natural compoundin vitro: bufalin remarkably inhibited growth in human gallbladder cancer cells by decreasing cell proliferation, inducing cell cycle arrest and apoptosis in a dose-dependent manner. Bufalin also disrupted the mitochondrial membrane potential (ΔΨm) and regulated the expression of cell cycle and apoptosis regulatory molecules. Activation of caspase-9 and the subsequent activation of caspase-3 indicated that bufalin may be inducing mitochondria apoptosis pathways [1]. bufalin suppressed the protein levels associated with DNA damage and repair, such as a DNA dependent serine/threonine protein kinase (DNA-PK), DNA repair proteins breast cancer 1, early onset (BRCA1), 14-3-3 σ (an important checkpoint keeper of DDR), mediator of DNA damage checkpoint 1 (MDC1), O6-ethylguanine-DNA methyltransferase (MGMT) and p53 (tumor suppressor protein) [2]. TNF-α significantly increased p65 translocation into nucleus (P 物理化学性质： CAS号：465-21-4 常用中文名：蟾毒灵 常用英文名：Bufalin 分子式：C24H34O4 分子量：386.524 密度：1.2±0.1 g/cm3 沸点：556.6±50.0 °C at 760 mmHg 熔点：242 - 243ºC 闪点：189.0±23.6 °C 储存条件：库房低温,通风,干燥,与食品原料分开存放 |
- 上海化源世纪贸易有限公司
- 上海市 上海市 普陀区
- 产品名：蟾毒灵
- 价格：
- 纯度：98.0%
- 备货期：10天
- 联系人：徐经理
- 云南西力生物技术股份有限公司
- 云南省 昆明市 盘龙区
- 产品名：蟾毒灵
- 价格： ￥需询单/5mg
- 纯度：98.0%
- 备货期：10天
- 联系人：郑雪平
- 四川恒诚致远生物科技有限公司
- 四川省 成都市 温江区
- 产品名：蟾毒灵
- 价格： ￥需询单/5mg ￥需询单/20mg ￥需询单/100mg ￥需询单/1g
- 纯度：98.0%
- 备货期：需询单
- 联系人：张半夏
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参考价格：$178/10mM*1mLinDMSO