长春碱
更新时间：2024-09-30 21:14:07
| 常用名 | 长春质碱 | CAS号 | 2468-21-5 |
|---|---|---|---|
| 价格 | ￥300.0/20mg | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 900 mg |
| 产品详情（用途，包装等）
用途： Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM.Target: nAChRCatharanthine evokes a concentration-dependent attenuation of carbachol responses in the rat ileum preparation, producing rightward curve displacements and decreases in maximal agonist responses. The mixture of serpentine, plus ajmalicine and catharanthine reveals a concentration-dependent inhibitory effect of acethylcholinesterase (AchE), with an IC50 at ca. 2.25 μg/Ml [1]. Catharanthine can induce the self-association of tubulin into linear indefinite polymers with an efficacy that is 75% that of vinblastine or vincristine. Catharanthine binds to tubulin alpha-beta dimer with binding constant of 2.8 mM [2]. Catharanthine stimulates release of amylase from pancreatic fragments and to cause extensive degranulation of pancreatic acinar cells with accumulation of membrane material in the Golgi region. Catharanthine induces a delayed release of Ca2+ from prelabeled pancreatic fragments as compared to bethanechol [3]. Catharanthine inhibits epibatidine-induced Ca(2+) influx in TE671-α, -β, -γ, -δ cells in a noncompetitive manner with similar potencies IC50 of 17 mM-25 mM. Catharanthine inhibits [3H]TCP binding to the desensitized Torpedo AChR with higher affinity compared to the resting AChR. Catharanthine enhances [3H]cytisine binding to resting but activatable Torpedo AChRs, suggesting desensitizing properties [4]. 物理化学性质： CAS号：2468-21-5 常用中文名：长春质碱 常用英文名：Catharanthine 分子式：C21H24N2O2 分子量：336.427 密度：1.3±0.1 g/cm3 沸点：491.5±45.0 °C at 760 mmHg 熔点：138-140ºC 闪点：251.1±28.7 °C 储存条件：库房低温通风干燥 |
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：长春质碱
- 价格： ￥218.0/20mg ￥298.0/20mg
- 纯度：98.0%
- 备货期：2天
- 联系人：刘佳
- 上海源溪生物科技有限公司
- 上海市 上海市 浦东新区
- 产品名：Catharanthine
- 价格： ￥需询单/1g
- 纯度：98.9%
- 备货期：1天
- 联系人：赖经理
- 上海阿摩尔生物科技有限公司
- 上海市 上海市 奉贤区
- 产品名：长春质碱
- 价格： ￥需询单/100mg ￥需询单/1g ￥需询单/250mg ￥需询单/50mg
- 纯度：98.0%
- 备货期：需询单
- 联系人：王汐瑶
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：长春质碱
- 价格： ￥273.9/20mg ￥需询单/1g ￥需询单/1g ￥需询单/1g
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$66/10mM*1mLinDMSO