4'-去甲氧基表鬼臼毒素
更新时间：2024-09-19 00:23:15
| 常用名 | 4'-去甲基表鬼臼毒素 | CAS号 | 6559-91-7 |
|---|---|---|---|
| 价格 | ￥300.0/20mg | 纯度 | 98.0% |
| 备货期 | 1天 | 库存 | 900 mg |
| 产品详情（用途，包装等）
用途： 4'-Demethylepipodophyllotoxin(4'-DMEP) is a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer drugs; a potent inhibitor of microtubule assembly.IC50 Value: 0.31uM(EC5 0in HL60 cell, MTT assay, 48h); 0.37uM(EC50 in HepG2 cell, MTT assay, 48h) [1]Target: microtubulein vitro: 4-TMP-DMEP showed strong cytotoxicity activity against the above-mentioned five tumor cell lines. The EC50s of 4-TMP-DMEP against these tumor cell lines ranged from 0.24 to 0.11 μM, which were 0.29 to 3618 times lower than that of DMEP [1].in vivo: Treatment of animals with DMEP (until the end of the experiment), 30 min before TPA treatment, significantly reduced the tumor incidence, tumor volume and the conversion efficiency of papillomas to squamous cell carcinomas. The tumor formation and growth was also delayed by DMEP pre-treatment [2]. 物理化学性质： CAS号：6559-91-7 常用中文名：4'-去甲基表鬼臼毒素 常用英文名：4'-Demethylepipodophyllotoxin 分子式：C21H20O8 分子量：400.379 密度：1.4±0.1 g/cm3 沸点：626.5±55.0 °C at 760 mmHg 熔点：246-248ºC 闪点：224.4±25.0 °C 储存条件：-20°C Freezer |
- 上海吉至生化科技有限公司
- 上海市 上海市 奉贤区
- 产品名：4'-去甲氧基表鬼臼毒素
- 价格： ￥298.0/20mg
- 纯度：98.0%
- 备货期：1天
- 联系人：刘佳
- 上海阿拉丁生化科技股份有限公司
- 上海市 上海市 浦东新区
- 产品名：4'-去甲基表鬼臼毒素
- 价格： ￥144.9/1g ￥53.9/250mg ￥1788.9/25g ￥84.9/500mg
- 纯度：98.0%
- 备货期：1天
- 联系人：阿拉丁
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参考价格：$66/10mM*1mLinDMSO