| 常用名 | α-细辛脑 | CAS号 | 2883-98-9 |
|---|---|---|---|
| 价格 | ¥168.0/20mg | 纯度 | 98.0% |
| 备货期 | 2天 | 库存 | 询单 |
| 产品详情(用途,包装等)
用途: Alpha-Asarone is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.IC50 value:Target:In vitro: The results indicated that α-asarone significantly attenuated the LPS-stimulated increase in neuroinflammatory responses and suppressed pro-inflammatory cytokine production in BV-2 cells. Mechanistic study revealed that α-asarone?inhibited the LPS-stimulated activation via regulation of nuclear factor kappa-B by blocking degradation of inhibitor kappa B-alpha signaling in BV-2 microglial cells. [2]In vivo: The present results reveal that the acute treatment of α-asarone elicited biphasic responses on immobility such that the duration of the immobility time is significantly reduced at lower doses (15 and 20 mg/kg, i.p.) but increased at higher doses (50 and 100 mg/kg, i.p.) in the TST. Besides, α-asarone at higher doses (50 and 100 mg/kg, i.p.) significantly decreased the spontaneous locomotor activity.[1] 物理化学性质: CAS号:2883-98-9 常用中文名:α-细辛脑 常用英文名:alpha-Asarone 分子式:C12H16O3 分子量:208.254 密度:1.0±0.1 g/cm3 沸点:296.0±0.0 °C at 760 mmHg 熔点:57-61 °C(lit.) 闪点:107.7±23.8 °C 储存条件:−20°C |